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促甲状腺激素α亚基
2020-03-26 18:29:21
1DZ7, 1E9J, 1FL7, 1HCN, 1HD4, 1HRP, 1QFW, 1XWD, 4AY9· signal transduction · cell-cell signaling · positive regulation of cell proliferation · gonad development · peptide hormone processing · positive regulation of cell migration · thyroid gland development · luteinizing hormone secretion · cellular response to hormone stimulus · cellular protein metabolic process · positive regulation of transcription from RNA polymerase II promoter · negative regulation of organ growth · follicle-stimulating hormone secretion糖蛋白激素α亚基(英语:Alpha subunit of glycoprotein hormones,或称为绒毛膜促性腺激素α亚基,Glycoprotein hormones alpha chain)是一个由人类基因CGA 编码的蛋白质。人体的四种糖蛋白激素(英语:glycoprotein hormones)--人绒毛膜促性腺激素(hCG)、黄体生成素(LH)、促卵泡激素(FSH)和促甲状腺激素(TSH)都是以同样的该α亚基和各自不同的β亚基组成的二聚体。此α链的92个氨基酸残基的序列为:NH2 - Ala - Pro - Asp - Val - Gln - Asp - Cys - Pro - Glu - Cys - Thr - Leu - Gln - Glu - Asn - Pro - Phe - Phe - Ser - Gln - Pro - Gly - Ala - Pro - Ile - Leu - Gln - Cys - Met - Gly - Cys - Cys - Phe - Ser - Arg - Ala - Tyr - Pro - Thr - Pro - Leu - Arg - Ser - Lys - Lys - Thr - Met - Leu - Val - Gln - Lys - Asn - Val - Thr - Ser - Glu - Ser - Thr - Cys - Cys - Val - Ala - Lys - Ser - Tyr - Asn - Arg - Val - Thr - Val - Met - Gly - Gly - Phe - Lys - Val - Glu - Asn - His - Thr - Ala - Cys - His - Cys - Ser - Thr - Cys - Tyr - Tyr - His - Lys - Ser - COOH糖蛋白激素α亚基引用了美国国家医学图书馆提供的资料,这些资料属于公共领域。

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